Slowing Alzheimer's
23 April 2025
A new medication for Alzheimer's disease, already used in the US, UK, and Japan, was approved by the European Commission last week. It's the first authorised treatment that targets the disease itself, rather than just its symptoms. Lecanemab antibody, its active ingredient, is directed against amyloid plaques: protein deposits that cause patients' brain cells to die over time.
The drug allows to slow down their build up, but not reverse it. That means only patients in the first stages can benefit from it. Others who have a specific gene variant also cannot use lecanemab, sold under the brand name Leqembi, due to its severe side effects: swelling and bleeding in the brain.
It's high time for an improved treatment against Alzheimer's: the number of people in the EU living with dementia, an umbrella term Alzheimer's falls under, is estimated to be over 7,8 million – one in 60 EU citizens. With an ageing population, the number will almost double by 2050 to 14,2 million in the EU.
![]() | Zuzanna Stawiska |
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